evaluation of neuroprotective effect of 1-benzyl-4-((6-alkoxy-3-oxobenzofuran-2(3h)-ylidene) methyl) pyridinium derivatives on beta amyloid (aβ) induced toxicity in pc12 cells

اسناد مشابه

• Decoding the Neuroprotective Potential of Methyl Gallate-Loaded Starch Nanoparticles against Beta Amyloid-Induced Oxidative Stress-Mediated Apoptosis: An In Vitro Study

  مقاله‌ی دسترسی آزاد۲۰۲۱PharmaceuticsNallasamyPrakashkumar, Bhagavathi SundaramSivamaruthi, ChaiyavatChaiyasut, NatarajanSuganthy

  Alzheimer's disease (AD) is a multifaceted neuronal disorder and a challenge to medical practitioners, as the blood-brain barrier (BBB) acts as a major obstacle for drug delivery to the brain. Development of a nanomaterial-based drug delivery system (DDS) paved a way to penetrate

• Potential neuroprotective of trans-resveratrol a promising agent tempeh and soybean seed coats-derived against beta-amyloid neurotoxicity on primary culture of nerve cells induced by 2-methoxyethanol

  مقاله‌ی دسترسی آزاد۲۰۲۲Brazilian Journal of Biology['Yulia Irnidayanti', 'D. R. Sutiono', 'Nabil A. Ibrahim', 'Popi Hadi Wisnuwardhani', 'Agus Santoso', '']

  Resveratrol, a natural polyphenol found in tempeh, has not been investigated especially in vitro as a neuroprotective agent against 2-methoxyethanol (2-ME)-induced beta-amyloid cytotoxicity. Beta amyloid peptides (Aβ) could initiate neurotoxic events and neuron-inflammatory respo

• Neuroprotective Properties of Gallic Acid from Sanguisorbae Radix on Amyloid .BETA. Protein (25-35)-Induced Toxicity in Cultured Rat Cortical Neurons

  مقاله‌ی دسترسی آزاد۲۰۰۸Biological and Pharmaceutical BulletinJu YeonBan, Ha Thi ThuyNguyen, Hee-JuLee, Soon OckCho

  Our previous studies reported that methanol extract of Sanguisorbae radix from Sanguisorba officinalis L. (Rosaceae) prevented neuronal cell damage induced by Abeta (25-35) in vitro. The present study was carried out to investigate the effect of gallic acid isolated from Sanguiso

• Neuroprotective properties of gallic acid from Sanguisorbae radix on amyloid beta protein (25--35)-induced toxicity in cultured rat cortical neurons.

  سند علمی۲۰۰۸Biological & pharmaceutical bulletinJu Yeon Ban, Ha Thi Thuy Nguyen, Hee-Ju Lee, Soon Ock Cho

  Our previous studies reported that methanol extract of Sanguisorbae radix from Sanguisorba officinalis L. (Rosaceae) prevented neuronal cell damage induced by Abeta (25-35) in vitro. The present study was carried out to investigate the effect of gallic acid isolated from Sanguiso

• بررسی اثرات مشتقات 1-benzyl-4-((6-alkoxy-3-oxobenzofuran-2(3h)-ylidene)methyl) pyridinium بر تجمع پپتید بتا آمیلوئید و سمیت ناشی از آن در مدل in vitro

  پایان‌نامه۲۰۱۳وزارت علوم، تحقیقات و فناوری - دانشگاه تربیت مدرس - دانشکده علوم پزشکیزلیخا گلیج

  چکیده: بیماری آلزایمر یک بیماری نورودجنرتیو وابسته به سن است که با از بین رفتن نورونهای کولینرژیک و تاثیر بر حافظه و یادگیری مشخص میشود. بنابراین استفاده از مهارکنندههای آنزیم استیل کولین استراز(ache) میتواند علائم آن را بهبود ببخشد.مشتقات بنزوفورانون- ایلیدن- متیل بنزیل پیریدینی